PHILADELPHIA -- Forced out of the Phillies' 5-2 loss after four innings with a bruised right hand, it's unknown if Cole Hamels will make his next start.

With one in the fourth inning, Red Sox slugger Adrian Gonzalez scalded a ball that hit Hamels around the heel of his glove, causing it to fly off. The lefty recovered the ball and was able to get Gonzalez at first base for the second out of the frame.

Following a visit from manager Charlie Manuel, pitching coach Rich Dubee and the training staff, Hamels stayed in the game to get Dustin Pedroia to ground out and end the frame.

The lefty didn't return for the fifth, exiting with a bruised right hand. X-rays were negative, but there's a chance Hamels may miss his next start due to swelling in his hand.

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"It's not a slam dunk that he will [start]," general manager Ruben Amaro said.

According to Amaro, Hamels boarded the team bus to the airport to travel to Toronto with a few stitches in his right hand and wearing a soft splint.

Hamels, who deftly fielded a Marco Scutaro liner in the third, declined comment in the clubhouse.

Amaro said Hamels had a hard time holding his glove and gripping a bat. Dubee was concerned Hamels wouldn't be able to defend himself if a third line drive came jolting back at him.

"He wanted to stay in there. He wanted to pitch," Amaro said. "It was a good move. I'm glad he did it."

Hamels was replaced by David Herndon at the start of the fifth.

"At first, we thought it was all right," said Herndon, who took the loss, yielding three runs on five hits over two innings. "We're sitting there in the bullpen and he finished the inning, so I'm like, 'All right, he's going to go a few more.'"

Any time Hamels may miss would be another blow to a pitching staff depleted by injuries.

Starters Roy Oswalt and Joe Blanton are on the 15-day disabled list, as are relievers Ryan Madson, Brad Lidge and Jose Contreras.