CHICAGO -- Cubs manager Rick Renteria took advantage of expanded instant replay to challenge a call at first base in the sixth inning on Wednesday, and it was overturned to give Chicago its seventh run.

The Cubs had runners at first and third with one out and a 6-1 lead over the Pirates in the sixth. Junior Lake hit a grounder to third baseman Pedro Alvarez, who threw to Neil Walker at second for the force, who fired to first baseman Travis Ishikawa for the double play. First-base umpire Mark Carlson called Lake out on the close play at first, but Renteria challenged the call in what would have been his last opportunity to do so before the umpires gained sole discretion.

After a one-minute review, the call was overturned, and Lake was credited with a fielder's choice and RBI to give Chicago a 7-1 lead.

In the Pirates' ninth, Russell Martin hit a ball into the basket rimming the center-field bleachers, which was called a home run. The umpires reviewed the call, and it was confirmed. It was Martin's second homer of the game, but not enough as the Cubs won, 7-5.