Teams 
| Name | Opponent | Date |
|---|---|---|
| No-hitters | ||
| Roy Halladay (Perfect Game) | at Florida | May 29, 2010 |
| Kevin Millwood | vs. San Francisco | Apr. 27, 2003 |
| Tommy Greene | at Montreal | May 23, 1991 |
| Terry Mulholland | vs. San Francisco | Aug. 15, 1990 |
| Rick Wise | at Cincinnati | June 23, 1971 |
| Jim Bunning (Perfect Game) | at New York | June 21, 1964 |
| Johnny Lush | at Brooklyn | May 1, 1906 |
| Charles Fraser | at Chicago | Sept. 18, 1903 |
| Red Donahue | vs. Boston | July 8, 1898 |
| Charles Ferguson | vs. Providence | Aug. 29, 1885 |
| Extra-inning grand slams | ||
| Dale Murphy | vs. Chicago (11th) | Aug. 6, 1991 |
| John Kruk | vs. St. Louis (12th) | Sept. 17, 1989 |
| Mike Schmidt | at Cincinnati (11th) | July 11, 1983 |
| Deron Johnson | at New York (11th) | June 20, 1971 |
| Rick Joseph | vs. Los Angeles (11th) | Sept. 16, 1967 |
| Wally Post | vs. Los Angeles (10th) | Sept. 9. 1958 |
| Cy Williams | vs. Chicago (10th) | July 18, 1925 |
| Cy Williams | vs. New York (10th) | Sept. 4, 1924 |
| Four homers in a game | ||
| Mike Schmidt | at Chicago | Apr. 17, 1976 |
| Chuck Klein | at Pittsburgh | July 10, 1936 |
| Ed Delahanty | vs. Chicago | July 13, 1896 |
| Inside-the-park grand slams | ||
| Ted Kazanski | at New York | Aug. 8, 1956 |
| Willie Jones | at Pittsburgh | June 19, 1951 |
| George Harper | vs. Chicago | July 25, 1924 |
| Irish Meusel | at Cincinnati | Aug. 23, 1918 |
| Hitting for the cycle | ||
| David Bell | vs. Montreal | June 28, 2004 |
| Gregg Jeffries | vs. Los Angeles | Aug. 25, 1995 |
| Johnny Callison | at Pittsburgh | June 27, 1963 |
| Chuck Klein | at St. Louis | May 26, 1933 |
| Chuck Klein | vs. Chicago | July 1, 1931 |
| Cy Williams | at Pittsburgh | Aug. 5, 1927 |
| Sam Thompson | vs. Louisville | Aug. 17, 1894 |
| Lave Cross | at Brooklyn | Apr. 24, 1894 |
| Pinch hit grand slams | ||
| Jose Hernandez | vs. Chicago Cubs | Sept. 18, 2006 |
| Kevin Jordan | vs. Atlanta | Apr. 20, 2001 |
| Jim Eisenreich | vs. San Diego | Aug. 23, 1995 |
| Ozzie Virgil | vs. San Francisco | Sept. 2, 1983 |
| Bake McBride | vs. Montreal | July 8, 1978 |
| Dave Johnson | vs. Los Angeles | June 3, 1978 |
| Dave Johnson | vs. San Diego | Apr. 30, 1978 |
| Jim Hutto | vs. Los Angeles | July 19, 1970 |
| Rick Joseph | vs. Los Angeles | Sept. 16, 1967 |
| Roy Sievers | vs. Cincinnati | May 26, 1963 |
| Gene Freese | vs. Cincinnati | Apr. 18, 1959 |
| Vince DiMaggio | vs. Pittsburgh | June 2, 1945 |
| Jimmie Foxx | vs. St. Louis | May 18, 1945 |
| Schoolboy Rowe | vs. Boston | May 2, 1953 |
| Cy Williams | vs. Boston | Apr. 15, 1926 |
